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Home Veterinary Pharmacy Medicines Livestock Rx Excede For Swine 100ml
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Excede For Swine 100ml

$160.00 Original price was: $160.00.$150.00Current price is: $150.00.

Excede for Swine is a long-acting, single-dose antibiotic used to treat and control swine respiratory disease caused by key bacterial pathogens.

Purpose and Effectiveness

Excede for Swine is indicated for the treatment and coExcede For Swinentrol of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, and Streptococcus suis. It is a broad-spectrum cephalosporin antibiotic that inhibits bacterial cell wall synthesis, making it bactericidal. Clinical studies have shown that a single dose significantly improves survival, reduces lung lesions, and lowers bacterial isolation rates compared to other antibiotics like Baytril, providing at least seven days of therapeutic plasma levels.

Excede for Swine is an antibiotic indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, and Streptococcus suis. Each ml of Excede for Swine contains ceftiofur crystalline free acid equivalent to 100 mg ceftiofur. Administer Excede for Swine by IM injection in the post-auricular region of the neck behind the ear.)

The usual recommended dosage is 1 ml suspension per 44 lbs body weight. Do not administer more than 2 ml per injection site. Injection volumes in excess of 2 ml may result in violative residues. Pigs heavier than 88 lbs will require more than one injection. Ready-to-use suspension. Shake well before using. Ceftiofur.

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Description

Buy Excede For Swine Online: The Definitive Veterinary Guide to Ceftiofur Crystalline Free Acid Extended-Release Kinetics, Swine Respiratory Disease Control, Single-Dose Efficacy, and Porcine Health

Managing swine respiratory disease (SRD), pleuropneumonia, atrophic rhinitis, and soft-tissue infections in commercial pig herds requires a dependable, broad-spectrum antimicrobial formulation that maintains prolonged therapeutic plasma and lung tissue concentrations from a single, low-stress injection.

When swine herds face outbreaks of Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, or Streptococcus suis, traditional daily-injection antibiotics demand frequent handling, causing severe stress, weight loss, labor overhead, and missed treatment intervals.

Left unmanaged, porcine respiratory disease complexes escalate rapidly, causing severe lung consolidation, high herd morbidity, high mortality rates, and devastating economic loss.

To deliver extended therapeutic efficacy and eliminate the need for multi-day handling during respiratory outbreaks, swine veterinarians and professional producers rely on advanced long-acting cephalosporin injectables. Excede for Swine (manufactured by Zoetis) is a premier, professional-grade extended-release sterile suspension powered by Ceftiofur Crystalline Free Acid (CCFA) at a high concentration of $100 text{mg/mL}$. Engineered specifically for pigs, a single injection delivers extended bactericidal activity against major swine respiratory pathogens.

Antimicrobial Pharmacology & Extended-Release Kinetics

Excede delivers a targeted, long-acting bactericidal mechanism designed to disrupt bacterial cell wall synthesis while maintaining sustained tissue retention:

                  [Excede for Swine 100mg/mL Injectable Suspension Administered]
                                              |
                   [Deep Subcutaneous (SQ) Injection Behind the Ear]
                                              |
               [Formation of an Extended-Release Crystalline Free Acid Depot]
                                              |
               -------------------------------------------------
              |                                                 |
     [PEPTIDOGLYCAN BLOCKADE]                   [EXTENDED TISSUE DIFFUSION]
  (Inhibits Bacterial Transpeptidases)          (Maintains CMI Levels Beyond 7 Days)
              |                                                 |
              v                                                 v
   [Destruction of Growing Cell Walls]          [Deep Penetration into Lung & Pleural Fluid]
   (Bactericidal Action on Pathogens)           (Neutralizes Actinobacillus & Pasteurella Strains)
              |                                                 |
              v                                                 v
   [Rapid Cessation of Infection]                [Minimized Animal Handling & Stress]
              |                                                 |
               ------------------------> <----------------=====
                                              |
                                              v
                   [Complete Eradication of Susceptible Porcine Pathogens]
                                              |
                   [Restoration of Normal Herd Health, Vigor, & Weight Gain]

1. Inhibition of Bacterial Cell Wall Synthesis

Ceftiofur is a third-generation cephalosporin possessing broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Like other $beta$-lactam antimicrobials, ceftiofur exerts bactericidal action by interfering with bacterial cell wall synthesis through the binding of essential penicillin-binding proteins ($text{PBPs}$), resulting in lytic destruction of actively dividing pathogens.

2. Extended Pharmacokinetic Profile (CCFA Technology)

  • Unique Crystalline Depot: Formulated as a crystalline free acid suspension, Excede creates a specialized subcutaneous depot behind the pig’s ear. The drug dissolves slowly, releasing ceftiofur into systemic circulation at therapeutic levels for up to 7 days from a single dose.

  • Targeted Lung Penetration: Reaches high concentrations quickly in pulmonary tissue and bronchial fluids, making it exceptionally effective against encapsulated respiratory pathogens.

Primary Clinical & Porcine Herd Indications

Excede for Swine is an essential therapeutic and metaphylactic tool for commercial swine operations and veterinary practitioners:

  • Swine Respiratory Disease (SRD): Treatment and control of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, and Bordetella bronchiseptica.

  • Herd Metaphylaxis During Outbreaks: Rapidly halts the progression of respiratory disease outbreaks across entire finishing floors or nursery units with a single handling event.

  • Post-Weaning Respiratory Protection: Protects high-stress groups transitioning into finishing units where environmental changes trigger disease flare-ups.

Recommended Administration and Dosing Protocols

To guarantee absolute sterility, proper suspension homogeneity, and patient safety, Excede must be administered strictly via subcutaneous injection behind the ear.

1.Vigorously Agitate Vial:Homogenization.

Vigorously shake the multi-dose vial for at least 15 to 30 seconds prior to extraction to ensure the crystalline suspension is completely uniform and redispersed.

2.Confirm Base of Ear Route:Site Selection.

Prepare the injection site. Excede for Swine must be administered strictly via subcutaneous (SQ) injection in the neck region behind the ear (in the loose skin fold).

3.Calculate Precise Body Weight Dose:Dosage Calculation.

Calculate volume strictly based on body weight. Standard dosage for swine respiratory disease is $5.0 text{mg}$ ceftiofur equivalent per kg ($2.27 text{mg per lb}$) of body weight, equivalent to $0.5 text{mL}$ of suspension per 10 kg ($22 text{lbs}$) body weight.

4.Observe Maximum Site Limits:Volume Limits.

For pigs weighing over $80 text{kg}$ ($176 text{lbs}$), split the dose and administer half behind each ear to ensure proper subcutaneous absorption. Never exceed $2.0 text{mL}$ per injection site.

Order Excede For Swine Injection Online

Dosing Reference Table

The table below outlines standard administration guidelines for Excede for Swine ($100 text{mg/mL}$):

Pig Weight Benchmark Standard Volume Required Injection Site Placement Approved Route Therapeutic Duration
Nursery Pigs ($10 – 20 text{kg}$ / $22 – 44 text{lbs}$) $0.5 text{mL}$ to $1.0 text{mL}$ Single site behind the ear Subcutaneous (SQ) Single dose provides 7 days coverage
Growing Pigs ($30 – 60 text{kg}$ / $66 – 132 text{lbs}$) $1.5 text{mL}$ to $3.0 text{mL}$ Split across both ears ($1.5 text{mL}$ max/site) Subcutaneous (SQ) Single dose provides 7 days coverage
Finishing / Adult Pigs ($80+ text{kg}$ / $176+ text{lbs}$) $4.0 text{mL}$ (Max per head) Split equally behind both ears ($2.0 text{mL}$ per ear) Subcutaneous (SQ) Single dose provides 7 days coverage

Clinical Safety, Withdrawal Periods, and Storage

  • Meat Withdrawal Period: Always adhere strictly to regional regulatory withdrawal windows prior to marketing animal products for human consumption. Note: Swine treated with Excede typically require a mandatory meat withholding period of 14 days post-injection; verify exact local product labeling.

  • Strict Subcutaneous Route: Do not administer Excede intravenously, intraperitoneally, or intramuscularly in swine. Subcutaneous injection behind the ear is critical for proper sustained-release kinetics.

  • Storage Parameters: Store unopened vials at controlled room temperature between 20°C and 25°C (68°F to 77°F), with brief excursions permitted up to 30°C. Protect from freezing. Once broached, use within standard aseptic container timeframes (typically 12 weeks).

Frequently Asked Questions (FAQ)

Why must Excede be injected behind the ear in pigs?

The loose skin fold behind the ear provides the specialized subcutaneous fat and tissue architecture required for the crystalline free acid to form a stable depot and release ceftiofur slowly over 7 days. Injecting elsewhere alters absorption kinetics.

Can Excede for Swine be used to treat other livestock species?

Excede is specifically formulated and approved for swine respiratory disease. Other formulations of ceftiofur exist for cattle and horses, but specific dose rates and vehicle kinetics differ.

Does a single injection really last for a full week?

Yes. The crystalline free acid formulation dissolves gradually in subcutaneous tissue, maintaining bactericidal blood and lung tissue concentrations above minimum inhibitory thresholds for a full 7 days.

Where can I buy genuine Excede for Swine online?

You can safely purchase authentic, factory-sealed Excede for Swine online through Vet Pharma Med. We manage and store all veterinary pharmaceutical inventory under strict environmental controls to guarantee absolute product freshness, safety, and full potency.

Excede For Swine 100ml Injection For Sale Online

Secure Premium Sourcing from Vet Pharma Med

At Vet Pharma Med, we understand that controlling respiratory outbreaks and managing commercial swine herds requires absolute product reliability. Every vial of Excede for Swine is sourced through authorized veterinary distribution networks, stored in our climate-controlled warehouse, and shipped securely to ensure complete product quality.

For wholesale farm accounts, veterinary clinic supply orders, or logistics tracking assistance, please reach out to our professional support desk directly at our contact us page.

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