Buy Overxicam 50mL Solution Injection Online

Overxicam Injectable is a specialized veterinary formulation containing meloxicam, a highly regarded non-steroidal anti-inflammatory drug (NSAID) of the oxicam class. Formulated as a 50mL multi-dose sterile solution, Overxicam is designed for parenteral administration in cattle, horses, and swine. It delivers targeted anti-inflammatory, analgesic, and antipyretic activity, making it a critical therapeutic tool for managing acute respiratory infections, locomotor disorders, lameness, and post-operative inflammation in veterinary practice.

What Is Overxicam 50mL Solution Injection?

Overxicam Injectable contains meloxicam as its active pharmaceutical ingredient. Meloxicam is widely recognized in equine and livestock medicine for its preferential inhibition of the cyclooxygenase-2 (COX-2) enzyme, providing potent relief from pain, fever, and tissue inflammation while maintaining a favorable safety profile regarding gastrointestinal and renal mucosa compared to older non-selective NSAIDs.

The 50mL multi-dose vial presentation offers a practical, versatile volume for equine practitioners, livestock managers, and clinical veterinarians performing field interventions or hospital care.

Product Specifications Overview

Key Features and Benefits

• Preferential COX-2 Inhibition: Targets inflammatory prostaglandin synthesis while sparing COX-1 mediated physiological functions in the gut and kidneys.

• Triple Therapeutic Action: Delivers effective anti-inflammatory, analgesic, and antipyretic (fever-reducing) properties in a single dose.

• Extended Duration of Action: Provides sustained clinical relief, often requiring only once-daily or single-dose protocols depending on the species and indication.

• Supportive Therapy in Severe Infections: Reduces pulmonary tissue damage and systemic toxemia when co-administered with appropriate antimicrobial therapy in cattle respiratory disease or acute mastitis.

Mechanism of Action

Meloxicam acts at the biochemical level to interrupt the inflammatory cascade:

1. Inhibition of Prostaglandin Synthesis: Meloxicam preferentially inhibits the cyclooxygenase-2 (COX-2) isoenzyme, which is induced in response to tissue injury, cytokines, and endotoxins. This blocks the conversion of arachidonic acid into pro-inflammatory prostaglandins ($PGE_2$).

2. Anti-Exudative Effect: By decreasing prostaglandin levels, Meloxicam reduces capillary permeability and vascular exudation, curbing localized edema and soft tissue swelling.

3. Endotoxin Suppression: In cases of acute bacterial infections (such as coliform mastitis or severe pneumonia), Meloxicam inhibits the inflammatory response triggered by bacterial lipopolysaccharides (LPS).

Clinical Indications and Veterinary Uses

• Cattle:

  • Adjunctive therapy in acute Bovine Respiratory Disease (BRD) combined with suitable antibiotic treatment to reduce clinical signs and fever.

  • Management of acute clinical mastitis in combination with antimicrobial therapy.

  • Relief of post-diarrhea inflammation in young calves and musculoskeletal lameness.

• Horses:

  • Relief of inflammation and relief of pain in both acute and chronic musculoskeletal disorders (e.g., arthritis, laminitis, tendonitis).

  • Control of visceral pain associated with equine colic.

• Swine:

  • Reduction of fever and inflammation associated with Swine Respiratory Disease (SRD).

  • Adjunctive treatment of Mastitis-Metritis-Agalactia (MMA) syndrome in sows.

Administration and Dosage Guidelines

Note: Overxicam is a prescription veterinary product. Dosage and route must strictly follow regional product label directions or specific orders from a licensed veterinarian.

• Cattle: Typically administered as a single Subcutaneous (SQ) or Intravenous (IV) injection at 0.5 mg meloxicam per kg body weight (e.g., 2.5 mL per 100 kg body weight for a 20 mg/mL formulation).

• Horses: Administered via Intravenous (IV) injection at 0.6 mg meloxicam per kg body weight once daily for up to 14 days, depending on severity and regulatory approvals.

• Swine: Administered via Intramuscular (IM) injection as a single dose of 0.4 mg meloxicam per kg body weight, with the option for a second dose after 24 hours if clinically indicated.

Safety Information, Precautions, and Contraindications

+-----------------------------------------------------------------------------------+
|                                 SAFETY WARNING                                    |
|  Do not use in animals suffering from severe hepatic, cardiac, or renal dysfunction, |
|  or active gastrointestinal ulceration. Avoid concurrent use with other NSAIDs     |
|  or systemic corticosteroids. Strictly adhere to milk and meat withdrawal times.  |
+-----------------------------------------------------------------------------------+

• Dehydration Risk: Avoid treating severely dehydrated, hypovolemic, or hypotensive animals with NSAIDs, as this elevates the risk of renal toxicity.

• Concomitant Drug Therapy: Do not administer concurrently or within 24 hours of other NSAIDs (e.g., phenylbutazone, flunixin meglumine) or corticosteroids.

• Pregnancy & Lactation: Use in pregnant or breeding animals should be based on a benefit-risk assessment by the attending veterinarian, as safety in late gestation varies by species.

• Statutory Withdrawal Periods: Always observe statutory meat and milk withholding periods established in your jurisdiction for food-producing animals.

Storage and Handling Requirements

• Temperature Control: Store at controlled room temperature between 15°C and 25°C (59°F to 77°F). Protect from freezing.

• Light Protection: Keep the vial inside its original cardboard packaging to protect the solution from direct sunlight.

• Aseptic Technique: Clean the rubber stopper prior to each withdrawal and use sterile needles to preserve the sterility of the multi-dose container.

Purchasing Regulated Veterinary Medications Online

When procuring prescription anti-inflammatory injectables online for equine and livestock care:

• Valid Prescription Required: Authentic outlets require a valid prescription from a licensed veterinary professional.

• Chain of Custody: Ensure products are supplied via legitimate pharmaceutical channels to guarantee correct concentration and active purity.

• Regulatory Compliance: Verify that ordering complies with regional livestock drug guidelines and import regulations.

Where To Buy Overxicam 50mL Solution Injection Online

World Equine Vet provides access to verified, manufacturer-sourced veterinary pharmaceuticals, anti-inflammatory therapies, and clinical consumables for livestock operations and equine practices around the globe.

• Purchase genuine Overxicam 50mL Solution Injection with guaranteed batch traceability.

• Submit prescriptions smoothly and coordinate international fulfillment with our knowledgeable customer care team.

• Benefit from secure packaging and reliable, transparent shipping logistics.

Visit World Equine Vet today to explore our complete range of veterinary anti-inflammatories, analgesics, and equine healthcare supplies.

Frequently Asked Questions (FAQs)

1. What is the active ingredient in Overxicam 50mL Injection?

Overxicam contains meloxicam, a non-steroidal anti-inflammatory drug (NSAID) known for its preferential COX-2 inhibition.

2. Can Overxicam be used in horses?

Yes. Meloxicam is widely used in horses for managing musculoskeletal pain, lameness, and inflammation, typically via intravenous administration under veterinary supervision.

3. How does Overxicam help cattle with respiratory disease?

When combined with appropriate antibiotics, Overxicam reduces fever, lung inflammation, and tissue exudation, allowing the animal to recover faster and maintain better feed intake.

4. Can Overxicam be given with other pain relievers like phenylbutazone or flunixin?

No. Overxicam should not be combined with other NSAIDs or corticosteroids, as doing so significantly increases the risk of gastrointestinal ulceration and renal damage.

5. What routes of administration are approved for Overxicam?

Depending on the species and regional product labeling, Overxicam can be given subcutaneously (SQ) or intravenously (IV) in cattle, intravenously (IV) in horses, and intramuscularly (IM) in swine.